Introduction to Rabies:
Rabies is known as a disease of dogs, it affect animals and spread in animals and humans. Some animal do not develop they may carry rabies virus and transmit it to other animals one of these are monkeys. Rabies affect brainstem, thalamus and spinal cord alter their normal function. When one get affected by this virus it take one week to show symptoms that is person become wild or bite, it develop hydrophobia( fear of water, person not able to drink water even he is too much thirsty. According to some research this is because their neck muscle gets paralyzed), depression.
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History of Disease:
If we move back 2000 year, this disease is fatal. At that time if a dog is affected from this virus it would be killed by people and if a person affected then it locked in a separate place. But its first written evidence present in 1930. In 1768, this disease increases the number of death in Boston and spread rapidly in South America.
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Vaccination of Rabies:
In 1885, a 9 years old boy got affected by rabies virus. He brought to Louis Pasteur great scientist at that time. He injected a vaccine that is never tested before into the joseph without knowing the consequences, as an experiment. He injected 13 injections and the result was surprising, symptoms disappeared. Afterward this was used as rabies vaccine.
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Present time Treatment:
Now a day’s vaccine is used to prevent rabies virus. If a person is bitten by a dog, it is not necessary to wait for symptoms to appeared and check whether the dog has rabies or not. The person is treated as rabies because it has no definitive test except the PCR of CSF. Treatment is simply clean the wound with soap and keep the wound open because rabies virus dead when it come in contact with air. According to some research UV light from sun also help in destroying the virus but it doesn’t have any evidence .
Milwaukee Protocol:
In 2004, a 15 years old girl named Jenna Giese from united state develops rabies. One day when she is coming back from church, she is bitten by a bat. The scratch was small so she ignored the scratch and went home, after a week she become anxious and show some other symptoms. She brought to hospital after three weeks doctor though of meningitis but the test report was negative. He was sent to children hospital Wisconsin in Wauwatosa. Dr. Willoughby took sample and sent this sample to Centers for Disease Control in Georgia. Reports confirmed she has rabies. Doctors said it is too late for vaccination and ask their parents to bring it to home so she may die easily. Dr. Willoughby was not willing to give her vaccination after his failure in 1970’s. He thought of an experiment, he stopped her brain activity a state of coma. Because in this condition heart is over stimulated by brain and eventually cause death. So he cut the connection and gave the body time to fight with virus. After 14 days, the girl wake up from coma and she is completely fine but she was like a newborn at the age of 15. She re-learned everything like walking, talking etc. She was first who alive after rabies without being vaccinated and was called as Medical Marvel. After this technique is also used not worldwide and is known as Milwaukee Protocol.
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